Letter from the Publisher ( 11/16/10 )
Thank you for visiting the DNAScribe Web site.
Our goal at DNAScribe is to bring you information that you are not likely to hear anywhere else about how certain gene variants have the potential to influence your health. Our goal is to help make it so that this information can be used right now in your physician’s office to predict what diseases or adverse drug responses you may be at risk for.
In this emerging science called “personalized medicine,” new genetic knowledge puts you in the driver’s seat of your health and well-being.
For example, if your physician identifies gene variants that place you at higher risk for certain diseases, then he or she can design disease monitoring programs to look for disease related predictive biomarkers early, before the clinical onset of a disease. Having this knowledge also means you have more choices for taking early action to prevent or delay disease onset. This action might be experimental, like making changes in diet or exercise routines, or it might mean taking a drug treatment on a regular basis that is known to prevent the disease you are at risk for.
Your physician can also use information about your gene variants to predict what drugs you may not respond well to or drugs you may have a potential adverse reaction to.
Don’t be surprised if your physician is not familiar with this knowledge. Physicians are learning about personalized medicine right now, just like the rest of us. Some physicians, along with some of the rest of us, will be reluctant to use this new knowledge. However, there is good reason for this reluctance.
Specifically, personalized medicine is still in the beta test phase. Like computers and computer software, we once had to use the new products in order to find out where the bugs were and also find out what applications would offer us the greatest benefit. For most of us, it took a real hands on effort to drive computer industry growth. Today, using computers is a pretty seamless event.
Personalized medicine is very similar in this regard. Scientists and physicians need to have patients use personalized medicine in order for them to understand how the new information we are learning about how gene variants, in combination with environmental factors, will influence our health or our response to drugs. They need our help in order to test this knowledge and get it ready for our seamless, everyday use.
One of DNAScribe’s main goals is to help scientists and physicians accomplish this task, by linking them to our readers. For example, if you are reading DNAScribe’s on-line newsletter and you are interested in finding out about studies related to a subject that interests you, we will either provide a direct link to a study on the subject or we will contact scientists for you who might have an interest in starting a study in your interest area.
I hope you enjoy reading this issue of DNAScribe and I look forward to hearing from you in the future!
Affymetrix (AFFX), located in Santa Clara, California, sells patented microarray products. In 2009, Affymetrix experienced revenues of $327.1 million dollars, as opposed to $410.2 Million dollars in 2008. The patented microarray products can be visualized as strands of selected deoxyribonucleic acid (DNA) molecules organized into segments called genes. These are attached to a glass slide…
Severe life threatening asthma occurs in U.S. children of Puerto Rican descent at an alarming rate and a genetic variant may be responsible for this problem. Scientists and physicians have teamed up to find out if the ß2AR gene variant, in combination with certain environmental factors, might be responsible for this problem. Early identification of…
Hockey star Ron Duguay meets with neurologist to learn more about APOE4 Gene Variant- Ron Duguay, played 12 seasons in the National Hockey League, mostly as a center for the New York Rangers. Duguay recently found out that he has one copy of the APOE4 gene, which is a gene variant that, in combination with…
Have you ever wondered why there is contradictory information about what foods we should and shouldn’t eat in order to prevent and control disease? It turns out that each individual may have their own genetic “toolbox” of gene variants that they can use in combination with bioactive food components to prevent chronic diseases they may…
Article Link: ABC News Video: Genetically Screening Tumors Publish Date: 11/01/2009 Description: Fighting Cancer by Genetically Screening Tumors According to an ABC news story in November 2009, Bill Schuette had tried chemotherapy — seven different kinds — but his lung cancer continued to grow. His doctor told him that they had exhausted every option —…
Teenagers are wired to experiment with their environments and find their comfort zone, often amidst chaotic and tumultuous settings. Our species survives as a result of their daring and their insight.
But what happens when things start to go wrong? How can a young person turn it around? What can they depend on? Can they depend on science for answers? Do we make the science accessible to them?
Plavix is prescribed for more than 25 million people globally and generates in excess of $9 billion dollars in annual sales. Yet, neither the U.S. Food and Drug Administration (FDA), nor the American Heart Association can provide definitive guidance to physicians for determining which patients that need antiplatelet therapy should take Plavix (or clopidogrel, the…